Microcoils for transport of magnetic beads

被引:57
作者
Ramadan, Q
Yu, C
Samper, V
Poenar, DP
机构
[1] Inst Microelect, Singapore 117685, Singapore
[2] Inst Bioengn & NanoTechnol, Singapore 138669, Singapore
[3] Nanyang Technol Univ, Sch Elect & Elect Engn, Ctr Microelect, Singapore 639798, Singapore
关键词
D O I
10.1063/1.2149150
中图分类号
O59 [应用物理学];
学科分类号
摘要
Integrated magnetic devices were fabricated, consisting of arrays of microcoils of a novel structure, embedded in a silicon substrate, with small conductors asymmetrically shaped and with ferromagnetic pillars made of a magnetic alloy (NiCoP) as magnetic cores. These structures generated large magnetic field gradients that very effectively attracted magnetic beads. By alternatively injecting currents in an array of such microcoils placed in a microfluidic chamber, magnetic beads were guided in different movement modes and step sizes in a continuous flow. (c) 2006 American Institute of Physics.
引用
收藏
页码:1 / 3
页数:3
相关论文
共 13 条
[1]
Development and Characterization of Microfluidic Devices and Systems for Magnetic Bead-Based Biochemical Detection [J].
Choi, Jin-Woo ;
Oh, Kwang W. ;
Han, Arum ;
Okulan, Nihat ;
Wijayawardhana, C. Ajith ;
Lannes, Chad ;
Bhansali, Shekhar ;
Schlueter, Kevin T. ;
Heineman, William R. ;
Halsall, H. Brain ;
Nevin, Joseph H. ;
Helmicki, Arthur J. ;
Henderson, H. Thurman ;
Ahn, Chong H. .
BIOMEDICAL MICRODEVICES, 2001, 3 (03) :191-200
[2]
Fabrication of magnetic microfiltration systems using soft lithography [J].
Deng, T ;
Prentiss, M ;
Whitesides, GM .
APPLIED PHYSICS LETTERS, 2002, 80 (03) :461-463
[3]
Manipulation of magnetic microbeads in suspension using micromagnetic systems fabricated with soft lithography [J].
Deng, T ;
Whitesides, GM ;
Radhakrishnan, M ;
Zabow, G ;
Prentiss, M .
APPLIED PHYSICS LETTERS, 2001, 78 (12) :1775-1777
[4]
Hafeli U., 1997, Scientific and Clinical Applications of Magnetic Carriers, DOI DOI 10.1007/s10439-009-9660-y
[5]
Continuous magnetophoretic separation of blood cells in microdevice format [J].
Han, KH ;
Frazier, AB .
JOURNAL OF APPLIED PHYSICS, 2004, 96 (10) :5797-5802
[6]
Continuous microfluidic immunomagnetic cell separation [J].
Inglis, DW ;
Riehn, R ;
Austin, RH ;
Sturm, JC .
APPLIED PHYSICS LETTERS, 2004, 85 (21) :5093-5095
[7]
Manipulation of biological cells using a microelectromagnet matrix [J].
Lee, H ;
Purdon, AM ;
Westervelt, RM .
APPLIED PHYSICS LETTERS, 2004, 85 (06) :1063-1065
[8]
Integrated microfluidic isolation platform for magnetic particle manipulation in biological systems [J].
Mirowski, E ;
Moreland, J ;
Russek, SE ;
Donahue, MJ .
APPLIED PHYSICS LETTERS, 2004, 84 (10) :1786-1788
[9]
Lymphocyte fractionation using immunomagnetic colloid and a dipole magnet flow cell sorter [J].
Moore, LR ;
Zborowski, M ;
Sun, LP ;
Chalmers, JJ .
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, 1998, 37 (1-2) :11-33
[10]
On-chip micro-electromagnets for magnetic-based bio-molecules separation [J].
Ramadan, Q ;
Samper, V ;
Poenar, D ;
Yu, C .
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2004, 281 (2-3) :150-172