Adult Neurogenesis in Humans

被引：189

作者：

Bergmann, Olaf ^{[1
]}

Spalding, Kirsty L. ^{[1
]}

Frisen, Jonas ^{[1
]}

机构：

[1] Karolinska Inst, Dept Cell & Mol Biol, SE-17177 Stockholm, Sweden

来源：

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2015年 / 7卷 / 07期

基金：

欧洲研究理事会; 瑞典研究理事会;

关键词：

NEURAL STEM-CELLS; ROSTRAL MIGRATORY STREAM; OLFACTORY-BULB VOLUME; PROGENITOR CELLS; HIPPOCAMPAL NEUROGENESIS; HUMAN BRAIN; SUBVENTRICULAR ZONE; DENTATE GYRUS; NEURONS; NUMBER;

D O I：

10.1101/cshperspect.a018994

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Adult neurogenesis appears very well conserved among mammals. It was, however, not until recently that quantitative data on the extent of this process became available in humans, largely because of methodological challenges to study this process in man. There is substantial hippocampal neurogenesis in adult humans, but humans appear unique among mammals in that there is no detectable olfactory bulb neurogenesis but continuous addition of new neurons in the striatum.

引用

页数：12

共 74 条

[1]

Activation of adult-born neurons facilitates learning and memory [J].

Alonso, Mariana ;

Lepousez, Gabriel ;

Wagner, Sebastien ;

Bardy, Cedric ;

Gabellec, Marie-Madeleine ;

Torquet, Nicolas ;

Lledo, Pierre-Marie .

NATURE NEUROSCIENCE, 2012, 15 (06) :897-U127

[2]

Evolution of the base of the brain in highly encephalized human species [J].

Bastir, Markus ;

Rosas, Antonio ;

Gunz, Philipp ;

Pena-Melian, Angel ;

Manzi, Giorgio ;

Harvati, Katerina ;

Kruszynski, Robert ;

Stringer, Chris ;

Hublin, Jean-Jacques .

NATURE COMMUNICATIONS, 2011, 2

[3]

Proliferating cells can differentiate into neurons in the striatum of normal adult monkey [J].

Bédard, A ;

Cossette, M ;

Lévesque, M ;

Parent, A .

NEUROSCIENCE LETTERS, 2002, 328 (03) :213-216

[4]

The rostral migratory stream in adult squirrel monkeys:: contribution of new neurons to the olfactory tubercle and involvement of the antiapoptotic protein Bcl-2 [J].

Bédard, A ;

Lévesque, M ;

Bernier, PJ ;

Parent, A .

EUROPEAN JOURNAL OF NEUROSCIENCE, 2002, 16 (10) :1917-1924

[5]

Ben Abdallah, Nada M. -B. ;

Slomianka, Lutz ;

Vyssotski, Alexei L. ;

Lipp, Hans-Peter .

NEUROBIOLOGY OF AGING, 2010, 31 (01) :151-161

[6]

The Age of Olfactory Bulb Neurons in Humans [J].

Bergmann, Olaf ;

Liebl, Jakob ;

Bernard, Samuel ;

Alkass, Kanar ;

Yeung, Maggie S. Y. ;

Steier, Peter ;

Kutschera, Walter ;

Johnson, Lars ;

Landen, Mikael ;

Druid, Henrik ;

Spalding, Kirsty L. ;

Frisen, Jonas .

NEURON, 2012, 74 (04) :634-639

[7]

Evidence for Cardiomyocyte Renewal in Humans [J].

Bergmann, Olaf ;

Bhardwaj, Ratan D. ;

Bernard, Samuel ;

Zdunek, Sofia ;

Barnabe-Heider, Fanie ;

Walsh, Stuart ;

Zupicich, Joel ;

Alkass, Kanar ;

Buchholz, Bruce A. ;

Druid, Henrik ;

Jovinge, Stefan ;

Frisen, Jonas .

SCIENCE, 2009, 324 (5923) :98-102

[8]

Neocortical neurogenesis in humans is restricted to development [J].

Bhardwaj, Ratan D. ;

Curtis, Maurice A. ;

Spalding, Kirsty L. ;

Buchholz, Bruce A. ;

Fink, David ;

Bjork-Eriksson, Thomas ;

Nordborg, Claes ;

Gage, Fred H. ;

Druid, Henrik ;

Eriksson, Peter S. ;

Frisen, Jonas .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (33) :12564-12568

[9]

Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression [J].

Boldrini, Maura ;

Santiago, Adrienne N. ;

Hen, Rene ;

Dwork, Andrew J. ;

Rosoklija, Gorazd B. ;

Tamir, Hadassah ;

Arango, Victoria ;

Mann, J. John .

NEUROPSYCHOPHARMACOLOGY, 2013, 38 (06) :1068-1077

[10]

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation [J].

Clelland, C. D. ;

Choi, M. ;

Romberg, C. ;

Clemenson, G. D., Jr. ;

Fragniere, A. ;

Tyers, P. ;

Jessberger, S. ;

Saksida, L. M. ;

Barker, R. A. ;

Gage, F. H. ;

Bussey, T. J. .

SCIENCE, 2009, 325 (5937) :210-213

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