Labelling a single particle for positron emission particle tracking using direct activation and ion-exchange techniques

被引:92
作者
Fan, X. [1 ]
Parker, D. J. [1 ]
Smith, M. D. [1 ]
机构
[1] Univ Birmingham, Sch Phys & Astron, Birmingham B15 2TT, W Midlands, England
基金
英国工程与自然科学研究理事会;
关键词
PEPT; tracer labelling; ion-exchange; tracer property; direct activation;
D O I
10.1016/j.nima.2006.03.015
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
Positron emission particle tracking (PEPT) is a non-invasive technique used for obtaining dynamic information within multiphase systems. It involves tracking a single radioactively labelled tracer particle. The tracking efficiency and representative of PEPT data are crucially dependent on the amount of radioactivity labelled in a single particle, as well as the physical and chemical properties of a tracer. This paper will discuss the effect of tracer properties on PEPT data and two labelling techniques, direct activation and ion-exchange, in detail. In direct activation, particles are directly bombarded using a 33 MeV He-3 beam. A few of the oxygen atoms in the particles are then converted into F-18 radioisotope. Direct activation can be used to label a particle with a size range from 1 to 10 mm, but the material must be able to resist a high temperature. The ion-exchange technique can be used to label smaller resin particles with a size ranging from 60 to 1000 mu m. The radioactivity labelled in a single resin bead is controlled by ion-exchange properties of the resin material, anions present in the radioactive water and processing time. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:345 / 350
页数:6
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