2-Pyridylsilyl group: A useful multifunctional group in organic synthesis

被引：33

作者：

Itami, K ^{[1
]}

Yoshida, J

机构：

[1] Nagoya Univ, Res Ctr Mat Sci, Nagoya, Aichi 4648602, Japan

[2] JST, PRESTO, Kawaguchi, Saitama 3320012, Japan

[3] Kyoto Univ, Dept Synthet Chem & Biol Chem, Grad Sch Engn, Kyoto 6158510, Japan

来源：

SYNLETT | 2006年 / 02期

关键词：

2-pyridylsilyl group; removable directing group; phase tag;

D O I：

10.1055/s-2005-923611

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The utility of the 2-pyridylsilyl group as a multifunctional group in organic synthesis is described. The use of the 2-pyridylsilyl group as a removable directing group is a powerful synthetic strategy that circumvents the specificity-generality dilemma in mental-mediated organic synthesis. In addition, the utility of the 2-pyridylsilyl group as a phase tag for strategic separation and as a removable hydrophilic group for aqueous reactions is also described.

引用

页码：157 / 180

页数：24

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