Tandem copper-catalysed aryl and alkenyl amination reactions: the synthesis of N-functionalised indoles

被引：42

作者：

Hodgkinson, Roy C. ^{[1
]}

Schulz, Jurgen

Willis, Michael C. ^{[1
]}

机构：

[1] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2009年 / 7卷 / 03期

基金：

英国工程与自然科学研究理事会;

关键词：

CROSS-COUPLING REACTIONS; C-N; BOND FORMATION; EFFICIENT SYNTHESIS; CONTAINING HETEROCYCLES; NITROGEN-HETEROCYCLES; ROOM-TEMPERATURE; PALLADIUM; HALIDES; AMIDATION;

D O I：

10.1039/b817254d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Cu-diamine complex effectively catalyses tandem C-N bond formation on 2-(2-haloalkenyl)-aryl halide substrates, to deliver a series of N-functionalised indoles. Anilines, amides and carbamates are all effective coupling partners under the developed conditions.

引用

页码：432 / 434

页数：3

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