A Michael initiated-condensation-elimination sequence for the stereoselective synthesis of maleate derivatives

被引：7

作者：

Harrowven, DC

Poon, HS

机构：

[1] Department of Chemistry, University of Southampton, Highfield, Southampton

来源：

TETRAHEDRON | 1996年 / 52卷 / 04期

关键词：

D O I：

10.1016/0040-4020(95)00965-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The paper describes a convenient method for the diastereoselective synthesis of trisubstituted alkenes through the lithium amide mediated union of ketones and diethyl maleate. The reaction has been shown to proceed via a Michael Initialed - Condensation - Elimination (MICE) sequence.

引用

收藏

页码：1389 / 1398

页数：10

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