Colorectal Cancer: Looking for Answers in the Microbiota

被引:86
作者
Jobin, Christian [1 ]
机构
[1] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA
关键词
D O I
10.1158/2159-8290.CD-13-0042
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
At a simplistic level, colorectal cancer arises from mutations in various proto-oncogenes and tumor suppressor genes. Aside from genetically inherited factors, environmental, lifestyle, and dietary habits have all been identified as risk agents promoting mutational events leading to the development of colorectal cancer. This "In Focus" presents evidence that the intestinal endogenous bacterial community represents a risk factor for the development of colorectal cancer. (C) 2013 AACR.
引用
收藏
页码:384 / 387
页数:4
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