Biosynthesis and attachment of novel bacterial polyketide synthase starter units

被引:250
作者
Moore, BS [1 ]
Hertweck, C
机构
[1] Univ Arizona, Coll Pharm, Div Med Chem, Tucson, AZ 85721 USA
[2] Hans Knoell Inst Nat Prod Res, D-07745 Jena, Germany
关键词
D O I
10.1039/b003939j
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The biosynthesis and mode of attachment of a wide range of polyketide synthase (PKS) starter units in bacteria are covered in this review. Natural, unnatural, and engineered starter units associated with type I and type II PKSs are reported. The literature through early 2001 is reviewed, and 240 references cited.
引用
收藏
页码:70 / 99
页数:30
相关论文
共 243 条
[81]   A plant-like biosynthesis of benzoyl-CoA in the marine bacterium 'Streptomyces maritimus' [J].
Hertweck, C ;
Moore, BS .
TETRAHEDRON, 2000, 56 (46) :9115-9120
[82]   Investigation of glycerol incorporation into soraphen A [J].
Hill, AM ;
Harris, JP ;
Siskos, AP .
CHEMICAL COMMUNICATIONS, 1998, (21) :2361-2362
[83]   OCCURRENCE IN SOIL OF THERMO-ACIDOPHILIC BACILLI POSSESSING OMEGA-CYCLOHEXANE FATTY-ACIDS AND HOPANOIDS [J].
HIPPCHEN, B ;
ROLL, A ;
PORALLA, K .
ARCHIVES OF MICROBIOLOGY, 1981, 129 (01) :53-55
[84]   Catalytic self-acylation of type II polyketide synthase acyl carrier proteins [J].
Hitchman, TS ;
Crosby, J ;
Byrom, KJ ;
Cox, RJ ;
Simpson, TJ .
CHEMISTRY & BIOLOGY, 1998, 5 (01) :35-47
[85]  
Hofle G., 1995, SEKUNDARMETABOLISMUS, P61
[86]   Genetic contributions to understanding polyketide synthases [J].
Hopwood, DA .
CHEMICAL REVIEWS, 1997, 97 (07) :2465-2497
[87]   R1128 SUBSTANCES, NOVEL NONSTEROIDAL ESTROGEN-RECEPTOR ANTAGONISTS PRODUCED BY A STREPTOMYCES .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES [J].
HORI, Y ;
ABE, Y ;
EZAKI, M ;
GOTO, T ;
OKUHARA, M ;
KOHSAKA, M .
JOURNAL OF ANTIBIOTICS, 1993, 46 (07) :1055-1062
[88]   R1128 SUBSTANCES, NOVEL NONSTEROIDAL ESTROGEN-RECEPTOR ANTAGONISTS PRODUCED BY A STREPTOMYCES .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURE DETERMINATION [J].
HORI, Y ;
TAKASE, S ;
SHIGEMATSU, N ;
GOTO, T ;
OKUHARA, M ;
KOHSAKA, M .
JOURNAL OF ANTIBIOTICS, 1993, 46 (07) :1063-1068
[89]  
HU Y, 2000, THESIS U WASHINGTON
[90]   3-amino-4-hydroxybenzoic acid: The precursor of the C7N unit in asukamycin and manumycin [J].
Hu, YD ;
Melville, CR ;
Gould, SJ ;
Floss, HG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (18) :4301-4302