Studies on novel synthetic methodologies, part 67.: (Bromodimethyl)sulfonium bromide catalyzed one-pot synthesis of α-aminonitriles

被引：48

作者：

Das, B ^{[1
]}

Ramu, R ^{[1
]}

Ravikanth, B ^{[1
]}

Reddy, KR ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2006年 / 9卷 / 09期

关键词：

alpha-aminonitriles; carbonyl compounds; amines; trimethylsilyl cyanide; (bromodimethyl)sulfonium bromide;

D O I：

10.1055/s-2006-926421

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel, simple and efficient one-pot synthesis of alpha-aminonitriles has been achieved by a three-component condensation of carbonyl compounds, amines and trimethylsilyl cyanide in the presence of (bromodimethyl)sulfonium bromide as a catalyst at room temperature. The products were obtained in high yields and in short reaction times.

引用

页码：1419 / 1422

页数：4

共 21 条

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