An intriguing effect of polymer-bound lithium amides in catalytic enantioselective rearrangement of meso-epoxides mediated by chiral lithium amides

被引：11

作者：

Asami, M ^{[1
]}

Seki, A ^{[1
]}

机构：

[1] Yokohama Natl Univ, Dept Adv Mat Chem, Grad Sch Engn, Hodogaya Ku, Yokohama, Kanagawa 2408501, Japan

来源：

CHEMISTRY LETTERS | 2002年 / 02期

关键词：

D O I：

10.1246/cl.2002.160

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Polymer-bound lithium dialkylamides were prepared from the corresponding polymer-bound amines and butyllithium. The reagent was successfully employed as an in situ regenerating agent of a chiral lithium amide in a catalytic enantioselective rearrangement of meso-epoxides, and chiral allylic alcohols were obtained in up to 95% ee.

引用

页码：160 / 161

页数：2

共 18 条

[11] ASYMMETRIC-SYNTHESIS MEDIATED BY CHIRAL LIGANDS [J].