Surfactant-assisted synthesis of nanoscale gadolinium metal-organic frameworks for potential multimodal imaging

被引:385
作者
Taylor, Kathryn M. L. [1 ]
Jin, Athena [1 ]
Lin, Wenbin [1 ]
机构
[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA
基金
美国国家科学基金会;
关键词
contrast agents; magnetic resonance imaging; metal-organic frameworks; nanoparticles; optical imaging;
D O I
10.1002/anie.200802911
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Less basic: By controlling the pH value of the reaction medium, two different gadolinium-containing nanoscale metal-organic frameworks (NMOFs) based on the same building blocks can be synthesized (see picture). The NMOFs carry a large payload of Gd3+ centers and are efficient contrast agents for T2-weighted magnetic resonance imaging. The NMOFs are highly luminescent when doped with other lanthanide ions such as Eu and Tb. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:7722 / 7725
页数:4
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