Harvesting canthinones: identification of the optimal seasonal point of harvest of Zanthoxylum chiloperone leaves as a source of 5-methoxycanthin-6-one

被引:14
作者
Cebrian-Torrejon, Gerardo [1 ]
Kablan, Landry [1 ]
Elena Ferreira, Maria [2 ]
Rodriguez de la Cruz, David [3 ]
Domenech-Carbo, Antonio [4 ]
Vera de Bilbao, Ninfa [2 ]
Rojas de Arias, Antonieta [5 ]
Figadere, Bruno [1 ]
Poupon, Erwan [1 ]
Fournet, Alain [6 ]
机构
[1] Univ Paris 11, Fac Pharm, Lab Pharmacognosie Associe CNRS, UMR BioCIS 8076, F-92296 Chatenay Malabry, France
[2] Univ Nacl Asuncion, Dept Trop Med, Inst Invest Ciencias Salud Asuncion, Asuncion, Paraguay
[3] Univ Salamanca, Hispano Luso Agr Res Ctr CIALE, Villamayor 37185, Salamanca, Spain
[4] Univ Valencia, Dept Quim Analit, Burjassot 46100, Valencia, Spain
[5] Ctr Desarrollo Invest Cientif CEDIC FMB Diaz Gill, Asuncion, Paraguay
[6] Fac Pharm Chatenay Malabry, IRD UMR 217, Lab Pharmacognosie, F-92296 Chatenay Malabry, France
关键词
alkylamide; canthinone; phytochemistry; benzylisoquinoline; alkaloids; HPLC-UV-MS; Rutaceae; MS-MS; sustainability; seasonality; Zanthoxylum chiloperone; electrochemistry; VAR; ANGUSTIFOLIUM; CANTHIN-6-ONE ALKALOIDS; CONSTITUENTS; AMIDES;
D O I
10.1080/14786419.2015.1022774
中图分类号
O69 [应用化学];
学科分类号
070301 [无机化学];
摘要
This article is focused on the seasonal variation in the contents of 5-methoxycanthin-6-one from the leaves of Zanthoxylum chiloperone (Rutaceae). Based on the pharmacological interest presented by 5-methoxycanthin-6-one, its seasonal variation in Z. chiloperone leaves was analysed in order to determine the best time for harvesting, optimising the 5-methoxycanthin-6-one content. The seasonal dynamics of canthinone alkaloids can be the key to improve the isolation from natural sustainable sources, such as leaves. Complementarily, this study describes the phytochemistry of leaf from this Ruraceae species.
引用
收藏
页码:2054 / 2058
页数:5
相关论文
共 22 条
[1]
Bai JH, 2009, PROC FL STATE HORTIC, V122, P308
[2]
Variation in the content of naphthoquinones in seeds and seedlings of Euclea natalensis [J].
Bapela, M. J. ;
Lall, N. ;
Isaza-Martinez, J. H. ;
Regnier, T. ;
Meyer, J. J. Marion .
SOUTH AFRICAN JOURNAL OF BOTANY, 2007, 73 (04) :606-610
[3]
The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum [J].
Cebrian-Torrejon, Gerardo ;
Spelman, Kevin ;
Leblanc, Karine ;
Munoz-Durango, Katalina ;
Gutierrez, Sandra Torijano ;
Ferreira, Maria Elena ;
de Arias, Antonieta Rojas ;
Figadere, Bruno ;
Fournet, Alain ;
Maciuk, Alexandre ;
Grellier, Philippe ;
Cech, Nadja B. ;
Poupon, Erwan .
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2011, 21 (04) :652-661
[4]
High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkamides and caffeic acid derivatives from Echinacea purpurea extracts [J].
Cech, NB ;
Eleazer, MS ;
Shoffner, LT ;
Crosswhite, MR ;
Davis, AC ;
Mortenson, AM .
JOURNAL OF CHROMATOGRAPHY A, 2006, 1103 (02) :219-228
[5]
dsDNA, ssDNA, G-quadruplex DNA, and nucleosomal DNA electrochemical screening using canthin-6-one alkaloid-modified electrodes [J].
Domenech-Carbo, Antonio ;
Cebrian-Torrejon, Gerardo ;
de Miguel, Laura ;
Tordera, Vicente ;
Rodrigues-Furtado, Daniel ;
Assad-Kahn, Suzana ;
Fournet, Alain ;
Figadere, Bruno ;
Vazquez-Manrique, Rafael P. ;
Poupon, Erwan .
ELECTROCHIMICA ACTA, 2014, 115 :546-552
[6]
Zanthoxylum chiloperone leaves extract: First sustainable Chagas disease treatment [J].
Elena Ferreira, Maria ;
Cebrian-Torrejon, Gerardo ;
Segovia Corrales, Alba ;
Vera de Bilbao, Ninfa ;
Rolon, Miriam ;
Vega Gomez, Celeste ;
Leblanc, Karine ;
Yaluf, Gloria ;
Schinini, Alicia ;
Torres, Susana ;
Serna, Elva ;
Rojas de Arias, Antonieta ;
Poupon, Erwan ;
Fournet, Alain .
JOURNAL OF ETHNOPHARMACOLOGY, 2011, 133 (03) :986-993
[7]
Effects of canthin-6-one alkaloids from Zanthoxylum chiloperone on Trypanosoma cruzi-infected mice [J].
Ferreira, Maria Elena ;
Nakayama, Hector ;
de Arias, Antonieta Rojas ;
Schinini, Alicia ;
de Bilbao, Ninfa Vera ;
Serna, Elva ;
Lagoutte, Delphine ;
Soriano-Agaton, Flor ;
Poupon, Erwan ;
Hocquemiller, Reynald ;
Fournet, Alain .
JOURNAL OF ETHNOPHARMACOLOGY, 2007, 109 (02) :258-263
[8]
Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium [J].
Ferreira, ME ;
de Arias, AR ;
de Ortiz, ST ;
Inchausti, A ;
Nakayama, H ;
Thouvenel, C ;
Hocquemiller, R ;
Fournet, A .
JOURNAL OF ETHNOPHARMACOLOGY, 2002, 80 (2-3) :199-202
[9]
Medicinal plants: Factors of influence on the content of secondary metabolites [J].
Gobbo-Neto, Leonardo ;
Lopes, Norberto P. .
QUIMICA NOVA, 2007, 30 (02) :374-381
[10]
Aliphatic acid amides of the fruits of Zanthoxylum piperitum [J].
Hatano, T ;
Inada, K ;
Ogawa, T ;
Ito, H ;
Yoshida, T .
PHYTOCHEMISTRY, 2004, 65 (18) :2599-2604