Nutrient transport across the placenta

被引：112

作者：

Knipp, GT

Audus, KL

Soares, MJ

机构：

[1] Univ Kansas, Med Ctr, Dept Mol & Integrat Physiol, Kansas City, KS 66160 USA

[2] Univ Kansas, Dept Pharmaceut Chem, Lawrence, KS 66045 USA

来源：

ADVANCED DRUG DELIVERY REVIEWS | 1999年 / 38卷 / 01期

基金：

美国国家卫生研究院;

关键词：

rat placenta; human placenta; nutrient transporters; amino acids; glucose; fatty acids; nucleoside;

D O I：

10.1016/S0169-409X(99)00005-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The placenta forms a selective barrier that functions to transport nutrients that are of critical use to the fetus. Nutrient transport across the placenta is regulated by many different active transporters found on the surface of both maternal and fetal facing membranes of the placenta. The presence of these transporters in the placenta has been implicated in the facilitation of nutrient diffusion and proper fetal growth. In this review, recent developments concerning nutrient transporters that regulate glucose, amino acid, fatty acid, and nucleoside transplacental movement are discussed. (C) 1999 Elsevier Science BN. All rights reserved.

引用

收藏

页码：41 / 58

页数：18

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