Stereoselective chemoenzymatic synthesis of both enantiomers of protected 4-amino-2-pentanone

被引：20

作者：

Besse, P ^{[1
]}

Ciblat, S

Canet, JL

Troin, Y

Veschambre, H

机构：

[1] Univ Blaise Pascal, Lab Synth Electrosynth & Etud Syst Interet Biol, CNRS, UMR 6504, F-63177 Aubiere, France

[2] Ecole Natl Super Chim Clermont Ferrand, Lab Chim Heterocycles & Glucides, EA 987, F-63174 Aubiere, France

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 11期

关键词：

D O I：

10.1016/S0957-4166(99)00234-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An acetal protected 4-amino-2-pentanone was synthesised by two different routes in 10 and seven steps, respectively, the key step being a microbiological reduction. Both enantiomers of the amine were obtained enantiomerically pure. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：2213 / 2224

页数：12

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