The model organism as a system: integrating 'omics' data sets

被引:468
作者
Joyce, AR
Palsson, BO
机构
[1] Univ Calif San Diego, Bioinformat Program, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA
关键词
D O I
10.1038/nrm1857
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Various technologies can be used to produce genome-scale, or 'omics', data sets that provide systems-level measurements for virtually all types of cellular components in a model organism. These data yield unprecedented views of the cellular inner workings. However, this abundance of information also presents many hurdles, the main one being the extraction of discernable biological meaning from multiple omics data sets. Nevertheless, researchers are rising to the challenge by using omics data integration to address fundamental biological questions that would increase our understanding of systems as a whole.
引用
收藏
页码:198 / 210
页数:13
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