Total synthesis of selected bioactive natural products: Illustration of strategy and design

被引:71
作者
Tatsuta, K [1 ]
Hosokawa, S [1 ]
机构
[1] Waseda Univ, Grad Sch Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan
关键词
D O I
10.1021/cr040630+
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A review on the elegant parts and significance of the total synthesis of useful bioactive compounds is presented. Enumerated and discussed are the total syntheses of cochleamycin A, natural products possessing fused aromatic rings, nitrogen-containing polyhydroxy compounds and trichostatin D. The total synthesis using both glycosylation under mitsunobu conditions and stereoselective vinylogous mukaiyama aldol reaction are also discussed.
引用
收藏
页码:4707 / 4729
页数:23
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