Glucose-triggered release using enzyme-gated mesoporous silica nanoparticles

被引：94

作者：

Aznar, Elena ^{[1
,2
]}

Villalonga, Reynaldo ^{[3
,4
]}

Gimenez, Cristina ^{[1
,2
]}

Sancenon, Felix ^{[1
,2
,5
]}

Dolores Marcos, M. ^{[1
,2
,5
]}

Martinez-Manez, Ramon ^{[1
,2
,5
]}

Diez, Paula ^{[3
]}

Pingarron, Jose M. ^{[3
,4
]}

Amoros, Pedro ^{[6
]}

机构：

[1] CIBER Bioingn Biomat & Nanomed, Madrid, Spain

[2] Univ Valencia, Univ Politecn Valencia, Unidad Mixta, Ctr Reconocimiento Mol & Desarrollo Tecnol IDM, Valencia, Spain

[3] Univ Complutense Madrid, Fac Chem, Dept Analyt Chem, E-28040 Madrid, Spain

[4] IMDEA Nanosci, Madrid 28049, Spain

[5] Univ Politecn Valencia, Dept Quim, Valencia 46022, Spain

[6] Univ Valencia, Inst Ciencia Mat ICMUV, Valencia 46071, Spain

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 57期

关键词：

RESPONSIVE CONTROLLED-RELEASE; HYDROGEN-PEROXIDE; GUEST MOLECULES; DELIVERY; SYSTEM; SUPPORTS;

D O I：

10.1039/c3cc42210k

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A new gated nanodevice design able to control cargo delivery using glucose as a trigger and cyclodextrin-modified glucose oxidase as a capping agent is reported.

引用

页码：6391 / 6393

页数：3

共 27 条

[1]

Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles [J].

Agostini, Alessandro ;

Mondragon, Laura ;

Bernardos, Andrea ;

Martinez-Manez, Ramon ;

Dolores Marcos, M. ;

Sancenon, Felix ;

Soto, Juan ;

Costero, Ana ;

Manguan-Garcia, Cristina ;

Perona, Rosario ;

Moreno-Torres, Marta ;

Aparicio-Sanchis, Rafael ;

Ramon Murguia, Jose .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (42) :10556-10560

[2]

Finely Tuned Temperature-Controlled Cargo Release Using Paraffin-Capped Mesoporous Silica Nanoparticles [J].

Aznar, Elena ;

Mondragon, Laura ;

Ros-Lis, Jose V. ;

Sancenon, Felix ;

Dolores Marcos, M. ;

Martinez-Manez, Ramon ;

Soto, Juan ;

Perez-Paya, Enrique ;

Amoros, Pedro .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (47) :11172-11175

[3]

Controlled release using mesoporous materials containing gate-like scaffoldings [J].

Aznar, Elena ;

Martinez-Manez, Ramon ;

Sancenon, Felix .

EXPERT OPINION ON DRUG DELIVERY, 2009, 6 (06) :643-655

[4]

Noninvasive continuous monitoring of physiological glucose using a monosaccharide-sensing contact lens [J].

Badugu, R ;

Lakowicz, JR ;

Geddes, CD .

ANALYTICAL CHEMISTRY, 2004, 76 (03) :610-618

[5]

Enzyme-Responsive Intracellular Controlled Release Using Nanometric Silica Mesoporous Supports Capped with "Saccharides" [J].

Bernardos, Andrea ;

Mondragon, Laura ;

Aznar, Elena ;

Marcos, M. Dolores ;

Martinez-Manez, Ramon ;

Sancenon, Felix ;

Soto, Juan ;

Barat, Jose Manuel ;

Perez-Paya, Enrique ;

Guillem, Carmen ;

Amoros, Pedro .

ACS NANO, 2010, 4 (11) :6353-6368

[6]

Triggered release in lipid bilayer-capped mesoporous silica nanoparticles containing SPION using an alternating magnetic field [J].

Bringas, Eugenio ;

Koysuren, Ozcan ;

Quach, Dat V. ;

Mahmoudi, Morteza ;

Aznar, Elena ;

Roehling, John D. ;

Dolores Marcos, M. ;

Martinez-Manez, Ramon ;

Stroeve, Pieter .

CHEMICAL COMMUNICATIONS, 2012, 48 (45) :5647-5649

[7]

Dual aperture control on pH- and anion-driven supramolecular nanoscopic hybrid gate-like ensembles [J].

Casasus, Rosa ;

Climent, Estela ;

Marcos, Ma. Dolores ;

Martinez-Manez, Ramon ;

Sancenon, Felix ;

Soto, Juan ;

Amoros, Pedro ;

Cano, Joan ;

Ruiz, Eliseo .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (06) :1903-1917

[8]

Controlled Delivery Using Oligonucleotide-Capped Mesoporous Silica Nanoparticles [J].

Climent, Estela ;

Martinez-Manez, Ramon ;

Sancenon, Felix ;

Marcos, Maria D. ;

Soto, Juan ;

Maquieira, Angel ;

Amoros, Pedro .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (40) :7281-7283

[9]

Controlled Delivery Systems Using Antibody-Capped Mesoporous Nanocontainers [J].

Climent, Estela ;

Bernardos, Andrea ;

Martinez-Manez, Ramon ;

Maquieira, Angel ;

Dolores Marcos, Maria ;

Pastor-Navarro, Nuria ;

Puchades, Rosa ;

Sancenon, Felix ;

Soto, Juan ;

Amoros, Pedro .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (39) :14075-14080

[10]

Gated Silica Mesoporous Supports for Controlled Release and Signaling Applications [J].

Coll, Carmen ;

Bernardos, Andrea ;

Martinez-Manez, Ramon ;

Sancenon, Felix .

ACCOUNTS OF CHEMICAL RESEARCH, 2013, 46 (02) :339-349

← 1 2 3 →