Importance of the debye screening length on nanowire field effect transistor sensors

被引：647

作者：

Stern, Eric

Wagner, Robin

Sigworth, Fred J.

Breaker, Ronald

Fahmy, Tarek M.

Reed, Mark A.

机构：

[1] Yale Univ, Dept Biomed Engn, New Haven, CT 06520 USA

[2] Yale Univ, Dept Elect Engn, New Haven, CT 06520 USA

[3] Yale Univ, Howard Hughes Med Inst, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA

[4] Yale Univ, Dept Appl Phys, New Haven, CT 06520 USA

来源：

NANO LETTERS | 2007年 / 7卷 / 11期

关键词：

D O I：

10.1021/nl071792z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanowire field effect transistors (NW-FETs) can serve as ultrasensitive detectors for label-free reagents. The NW-FET sensing mechanism assumes a controlled modification in the local channel electric field created by the binding of charged molecules to the nanowire surface. Careful control of the solution Debye length is critical for unambiguous selective detection of macromolecules. Here we show the appropriate conditions under which the selective binding of macromolecules is accurately sensed with NW-FET sensors.

引用

页码：3405 / 3409

页数：5

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