Enteropathogen Resource Integration Center (ERIC): bioinformatics support for research on biodefense-relevant enterobacteria

被引:11
作者
Glasner, Jeremy D. [1 ]
Plunkett, Guy, III [2 ]
Anderson, Bradley D. [1 ]
Baumler, David J. [1 ]
Biehl, Bryan S. [1 ]
Burland, Valerie [1 ,2 ]
Cabot, Eric L. [1 ]
Darling, Aaron E. [3 ]
Mau, Bob [1 ]
Neeno-Eckwall, Eric C. [1 ]
Pot, David [4 ]
Qiu, Yu [5 ]
Rissman, Anna I. [1 ]
Worzella, Sara [1 ]
Zaremba, Sam [4 ]
Fedorko, Joel [4 ]
Hampton, Tom [4 ]
Liss, Paul [1 ]
Rusch, Michael [1 ]
Shaker, Matthew [4 ]
Shaull, Lorie [4 ]
Shetty, Panna [4 ]
Thotakura, Silpa [4 ]
Whitmore, Jon [4 ]
Blattner, Frederick R. [1 ,2 ]
Greene, John M. [4 ]
Perna, Nicole T. [1 ,2 ]
机构
[1] Univ Wisconsin, Genome Ctr, Madison, WI 53703 USA
[2] Univ Wisconsin, Genet Lab, Madison, WI 53706 USA
[3] Univ Queensland, Inst Mol Biosci, St Lucia, Qld 4072, Australia
[4] SRA Int Inc, Rockville, MD 20852 USA
[5] Univ Calif San Diego, La Jolla, CA 92093 USA
关键词
D O I
10.1093/nar/gkm973
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ERIC, the Enteropathogen Resource Integration Center (www.ericbrc.org), is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefensediarrheagenic Escherichia coli, Shigella spp., Salmonella spp., Yersinia enterocolitica and Yersinia pestis. More than 30 genomes have been completely sequenced, many more exist in draft form and additional projects are underway. These organisms are increasingly the focus of studies using high-throughput experimental technologies and computational approaches. This wealth of data provides unprecedented opportunities for understanding the workings of basic biological systems and discovery of novel targets for development of vaccines, diagnostics and therapeutics. ERIC brings information together from disparate sources and supports data comparison across different organisms, analysis of varying data types and visualization of analyses in human and computer-readable formats.
引用
收藏
页码:D519 / D523
页数:5
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