Stereoselective syntheses of the C′D′E′F′-ring system of maitotoxin and the FG-ring system of gambierol

被引：56

作者：

Sakamoto, Y ^{[1
]}

Matsuo, G ^{[1
]}

Matsukura, H ^{[1
]}

Nakata, T ^{[1
]}

机构：

[1] RIKEN, Inst Phys & Chem Res, Wako, Saitama 3510198, Japan

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 17期

关键词：

D O I：

10.1021/ol016355k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The stereoselective syntheses of the C 'D 'E 'F ' -ring system of maitotoxin and the FG-ring system of gambierol were accomplished. The key steps involve 6-endo-cyclization of methylepoxide, Sml(2)-induced reductive cyclization, 6-endo-cyclization of vinylepoxide, and formation of the lactone ring.

引用

页码：2749 / 2752

页数：4

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