Deracemisation of α-amino acids -: (R)- and (S)-phenylalanine from the same enantiomer of a homochiral auxiliary

被引：16

作者：

Bull, SD ^{[1
]}

Davies, SG ^{[1
]}

Epstein, SW ^{[1
]}

Ouzman, JVA ^{[1
]}

机构：

[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 16期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0957-4166(98)00304-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Chiral auxiliary (3S)-N,N'-bis-(p-methoxybenzyl)-3-isopropylpiperazine-2,5-dione 1 was employed for the synthesis of both enantiomers of phenylalanine using a regioselective deprotonation/stereoselective reprotonation strategy. Modification of th is approach enables the efficient deracemisation of (+/-)-phenylalanine. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2795 / 2798

页数：4

共 16 条

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