Genomic Exploration of the Hemiascomycetous Yeasts:: 17.: Yarrowia lipolytica

被引：76

作者：

Casaregola, S ^{[1
]}

Neuvéglise, C

Lépingle, A

Bon, E

Feynerol, C

Artiguenave, F

Wincker, P

Gaillardin, C

机构：

[1] INA PG, CNRS,URA1925, INRA,UMR216, Lab Genet Mol & Cellulaire,Collect Levures Intere, F-78850 Thiverval Grignon, France

[2] Genoscope, Ctr Natl Sequencage, F-91057 Evry, France

来源：

FEBS LETTERS | 2000年 / 487卷 / 01期

关键词：

non-conventional yeast; transposable element; mitochondrial DNA; functional classification;

D O I：

10.1016/S0014-5793(00)02288-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A total of 4940 random sequence tags of the dimorphic yeast Yarrowia lipolytica , totalling 4.9 Mb, were analyzed. BLASTX comparisons revealed at least 1229 novel Y. lipolytica genes 1083 genes having homology with Saccharomyces cervisiae genes and 146 with genes from various other genomes. This confirms the rapid sequence evolution assumed for Y. lipolytica. Functional analysis of newly discovered genes revealed that several enzymatic activities were increased compared to S. cervisiae in particular, transport activities, ion homeostasis, and various metabolism pathways. Most of the mitochondrial genes were identified in contigs spanning more than 47 kb. Matches to retrotransposons were observed, including a S. cervisiae T33 and a LINE element. The sequences have been deposited with EMBL under the accession numbers AL409956-AL414895. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：95 / 100

页数：6

共 33 条

[1] Genomic exploration of the hemiascomycetous yeasts: 2. Data generation and processing [J].

Artiguenave, F ;

Wincker, P ;

Brottier, P ;

Duprat, S ;

Jovelin, F ;

Scarpelli, C ;

Verdier, J ;

Vico, V ;

Weissenbach, J ;

Saurin, W .

FEBS LETTERS, 2000, 487 (01) :13-16

[2] ARRANGEMENT OF THE RIBOSOMAL-RNA GENES IN SCHIZOSACCHAROMYCES-POMBE [J].

BARNITZ, JT ;

CRAMER, JH ;

ROWND, RH ;

COOLEY, L ;

SOLL, D .

FEBS LETTERS, 1982, 143 (01) :129-132

[3] Physiology and genetics of the dimorphic fungus Yarrowia lipolytica [J].

Barth, G ;

Gaillardin, C .

FEMS MICROBIOLOGY REVIEWS, 1997, 19 (04) :219-237

[4]

Barth G, 1996, NONCONVENTIONAL YEAS, P313

[5]

BECKERICH JM, 2000, INT MICROBIOL, V1, P123

[6] Genomic Exploration of the Hemiascomycetous Yeasts:: 4.: The genome of Saccharomyces cerevisiae revisited [J].

Blandin, G ;

Durrens, P ;

Tekaia, F ;

Aigle, M ;

Bolotin-Fukuhara, M ;

Bon, E ;

Casarégola, S ;

de Montigny, J ;

Gaillardin, C ;

Lépingle, A ;

Llorente, B ;

Malpertuy, A ;

Neuvéglise, C ;

Ozier-Kalogeropoulos, O ;

Perrin, A ;

Potier, S ;

Souciet, JL ;

Talla, E ;

Toffano-Nioche, C ;

Wésolowski-Louvel, M ;

Marck, C ;

Dujon, B .

FEBS LETTERS, 2000, 487 (01) :31-36

[7] Genomic organization of the yeast Yarrowia lipolytica [J].

Casaregola, S ;

Feynerol, C ;

Diez, M ;

Fournier, P ;

Gaillardin, C .

CHROMOSOMA, 1997, 106 (06) :380-390

[8] Genomic Exploration of the Hemiascomycetous Yeasts:: 7.: Saccharomyces servazzii [J].

Casaregola, S ;

Lépingle, A ;

Bon, E ;

Neuvéglise, C ;

Nguyen, HV ;

Artiguenave, F ;

Wincker, P ;

Gaillardin, C .

FEBS LETTERS, 2000, 487 (01) :47-51

[9] CLONING AND CHARACTERIZATION OF THE RIBOSOMAL-RNA GENES OF THE DIMORPHIC YEAST, YARROWIA-LIPOLYTICA [J].

CLARE, JJ ;

DAVIDOW, LS ;

GARDNER, DCJ ;

OLIVER, SG .

CURRENT GENETICS, 1986, 10 (06) :449-452

[10] CLONING AND SEQUENCING OF THE ALKALINE EXTRACELLULAR PROTEASE GENE OF YARROWIA-LIPOLYTICA [J].

DAVIDOW, LS ;

ODONNELL, MM ;

KACZMAREK, FS ;

PEREIRA, DA ;

DEZEEUW, JR ;

FRANKE, AE .

JOURNAL OF BACTERIOLOGY, 1987, 169 (10) :4621-4629

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