Nonlinear effects in the enantioselective 1,4-conjugate addition of diethylzinc to chalcone

被引：17

作者：

Hu, YC ^{[1
]}

Liang, XM ^{[1
]}

Zheng, Z ^{[1
]}

Hu, XQ ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 18期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetasy.2003.07.001

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A clear positive nonlinear effect of the enantiopurity of ligand 1 on the product ee was observed in the enantioselective 1,4-conjugate addition of Et2Zn to chalcone. The experimental data of nonlinear effect meet Kagan's ML2 model. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：2771 / 2774

页数：4

共 72 条

[1]

Alexakis A, 2000, EUR J ORG CHEM, V2000, P4011, DOI 10.1002/1099-0690(200012)2000:24<4011::AID-EJOC4011>3.0.CO

[2]

2-D

[3] Dramatic improvement of the enantiomeric excess in the asymmetric conjugate addition reaction using new experimental conditions [J].

Alexakis, A ;

Benhaim, C ;

Rosse, S ;

Humam, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (19) :5262-5263

[4]

Alexakis A, 2001, SYNLETT, P1375

[5] Acceleration of the conjugate addition of diethyl zinc to enones by either Cu(OTf)(2) or trivalent phosphorus ligands [J].

Alexakis, A ;

Vastra, J ;

Mangeney, P .

TETRAHEDRON LETTERS, 1997, 38 (44) :7745-7748

[6] Asymmetric conjugate addition of diethyl zinc to enones with tartrate chiral phosphite ligands [J].

Alexakis, A ;

Vastra, J ;

Burton, J ;

Mangeney, P .

TETRAHEDRON-ASYMMETRY, 1997, 8 (19) :3193-3196

[7] Asymmetric conjugate addition of diethyl zinc to enones with chiral phosphorus ligands derived from TADDOL [J].

Alexakis, A ;

Vastra, J ;

Burton, J ;

Benhaim, C ;

Mangeney, P .

TETRAHEDRON LETTERS, 1998, 39 (43) :7869-7872

[8] CHIRAL PHOSPHORUS LIGANDS FOR THE ASYMMETRIC CONJUGATE ADDITION OF ORGANOCOPPER REAGENTS [J].

ALEXAKIS, A ;

FRUTOS, J ;

MANGENEY, P .

TETRAHEDRON-ASYMMETRY, 1993, 4 (12) :2427-2430

[9]

Alexakis A, 2002, EUR J ORG CHEM, V2002, P3221

[10] Enantioselective catalytic conjugate addition of dialkylzinc reagents using copper-phosphoramidite complexes; Ligand variation and non-linear effects [J].

Arnold, LA ;

Imbos, R ;

Mandoli, A ;

de Vries, AHM ;

Naasz, R ;

Feringa, BL .

TETRAHEDRON, 2000, 56 (18) :2865-2878

← 1 2 3 4 5 6 7 8 →