Ceramic-based multisite microelectrode arrays for in vivo electrochemical recordings of glutamate and other neurochemicals

被引:41
作者
Burmeister, JJ
Gerhardt, GA [1 ]
机构
[1] Univ Kentucky, Albert B Chandler Med Ctr, Dept Anat & Neurobiol, Lexington, KY 40536 USA
[2] Univ Kentucky, Albert B Chandler Med Ctr, Dept Neurol, Ctr Sensor Technol, Lexington, KY 40536 USA
[3] Univ Kentucky, Albert B Chandler Med Ctr, Morris K Udall Parkinsons Dis Res Ctr Excellence, Lexington, KY 40536 USA
关键词
array; ceramic; choline; glutamate; microelectrodes; neurotransmitters;
D O I
10.1016/S0165-9936(03)00904-X
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Ceramic-based microelectrode arrays for electrochemical measures of neurochemicals in brain and spinal cord tissue are reviewed. Current fabrication procedures are explained, including discussions of various recording site layouts, insulating materials and recording strategies. Various coatings are employed to alter the sensitivity and the selectivity of the microelectrodes for the detection of certain neurochemicals. Several applications of these microelectrode arrays are discussed. (C) 2003 Published by Elsevier B.V.
引用
收藏
页码:498 / 502
页数:5
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