Alumina supported MoO3:: An efficient and reusable heterogeneous catalyst for synthesis of 3,4-dihydropyridine-2(1H)-ones under solvent free conditions

被引：64

作者：

Jain, Suman L. ^{[1
]}

Prasad, V. V. D. N. ^{[1
]}

Sain, Bir ^{[1
]}

机构：

[1] Indian Inst Petr, Chem & Biotechnol Div, Dehra Dun 248005, Uttar Pradesh, India

来源：

CATALYSIS COMMUNICATIONS | 2008年 / 9卷 / 04期

关键词：

biginelli reaction; 3,4-dihydropyrimidin-2(1H)-ones; solvent-free; heterogeneous catalysis; multicomponent reaction;

D O I：

10.1016/j.catcom.2007.04.021

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An efficient solvent free method for the synthesis of various 3,4-dihydropyrimidin-2(1H)-ones in excellent yields using alumina-supported MoO3 as recyclable heterogeneous catalyst is described. Compared to known methods, this new method provides an easy access to various 3,4-dihydropyrimidin-2(1H)-ones in excellent yields with shorter reaction times. Further the catalyst could be easily recovered from reaction mixture by filtration and is reusable. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：499 / 503

页数：5

共 37 条

[1] KA1(SO4)2•12H2O supported on silica gel as a novel heterogeneous system catalyzed biginelli reaction -: One-pot synthesis of di-hydropyrimidinones under solvent-free conditions [J].

Azizian, J ;

Mohammadi, AA ;

Karimi, AR ;

Mohammadizadeh, MR .

APPLIED CATALYSIS A-GENERAL, 2006, 300 (01) :85-88

[2]

BADEOUI HE, 2006, CATAL COMMUN, V6, P455

[3]

Bhosale RS, 2005, HETEROCYCL COMMUN, V11, P399

[4]

Biginelli P., 1893, GAZZ CHIM ITAL, V23, P360

[5] Silicagel supported sodium hydrogensulfate as a heterogenous catalyst for high yield synthesis of 3,4-dihydropyrimidin-2 (1H)-ones [J].

Chari, MA ;

Syamasundar, K .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2004, 221 (1-2) :137-139

[6] One-pot synthesis of dihydropyrimidinones using facile and reusable polyoxometalate catalysts for the Biginelli reaction [J].

Fazaeli, Razieh ;

Tangestaninejad, Shahram ;

Aliyan, Hamid ;

Moghadam, Majid .

APPLIED CATALYSIS A-GENERAL, 2006, 309 (01) :44-51

[7] A novel Cu-catalysed three-component one-pot synthesis of dihydro-pyrimidin-2(1H)-ones using microwaves under solvent-free conditions [J].

Gohain, M ;

Prajapati, D ;

Sandhu, JS .

SYNLETT, 2004, (02) :235-238

[8] Covalently anchored sulfonic acid onto silica as an efficient and recoverable interphase catalyst for the synthesis of 3,4-dihydropyrimidinones/thiones [J].

Gupta, Raman ;

Paul, Satya ;

Gupta, Rajive .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2007, 266 (1-2) :50-54

[9]

HERARI MM, 2006, CATAL COMMUN, V7, P370

[10] Unprecedented catalytic three component one-pot condensation reaction: An efficient synthesis of 5-alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones [J].

Hu, EH ;

Sidler, DR ;

Dolling, UH .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (10) :3454-3457

← 1 2 3 4 →