Alumina supported MoO3:: An efficient and reusable heterogeneous catalyst for synthesis of 3,4-dihydropyridine-2(1H)-ones under solvent free conditions

被引:64
作者
Jain, Suman L. [1 ]
Prasad, V. V. D. N. [1 ]
Sain, Bir [1 ]
机构
[1] Indian Inst Petr, Chem & Biotechnol Div, Dehra Dun 248005, Uttar Pradesh, India
关键词
biginelli reaction; 3,4-dihydropyrimidin-2(1H)-ones; solvent-free; heterogeneous catalysis; multicomponent reaction;
D O I
10.1016/j.catcom.2007.04.021
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
An efficient solvent free method for the synthesis of various 3,4-dihydropyrimidin-2(1H)-ones in excellent yields using alumina-supported MoO3 as recyclable heterogeneous catalyst is described. Compared to known methods, this new method provides an easy access to various 3,4-dihydropyrimidin-2(1H)-ones in excellent yields with shorter reaction times. Further the catalyst could be easily recovered from reaction mixture by filtration and is reusable. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:499 / 503
页数:5
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