Inlaid multi-walled carbon nanotube nanoelectrode arrays for electroanalysis

被引：118

作者：

Li, J ^{[1
]}

Koehne, JE ^{[1
]}

Cassell, AM ^{[1
]}

Chen, H ^{[1
]}

Ng, HT ^{[1
]}

Ye, Q ^{[1
]}

Fan, W ^{[1
]}

Han, J ^{[1
]}

Meyyappan, M ^{[1
]}

机构：

[1] NASA, Ames Res Ctr, Ctr Nanotechnol, Moffett Field, CA 94035 USA

来源：

ELECTROANALYSIS | 2005年 / 17卷 / 01期

关键词：

multi-walled carbon nanotubes; vertically aligned nanoelectrode array; chemical sensors; biosensors; DNA sensors; multiplex array; microchips;

D O I：

10.1002/elan.200403114

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The rapid development in nanomaterials and nanotechnologies has provided many new opportunities for electroanalysis. We review our recent results on the fabrication and electroanalytical applications of nanoelectrode arrays based on vertically aligned multi-walled carbon nanotubes (MWCNTs). A bottom-up approach is demonstrated, which is compatible with Si microfabrication processes. MWCNTs are encapsulated in SiO2 matrix leaving only the very end exposed to form inlaid nanoelectrode arrays. The electrical and electrochemical properties have been characterized, showing well-defined quasireversible nanoelectrode behavior. Ultrasensitive detection of small redox molecules in bulk solutions as well as immobilized at the MWCNT ends is demonstrated. A label-free affinity-based DNA sensor has shown extremely high sensitivity approaching that of fluorescence techniques. This platform can be integrated with microelectronics and microfluidics for fully automated microchips.

引用

页码：15 / 27

页数：13

共 63 条

[51] Synthesis of large arrays of well-aligned carbon nanotubes on glass [J].

Ren, ZF ;

Huang, ZP ;

Xu, JW ;

Wang, JH ;

Bush, P ;

Siegal, MP ;

Provencio, PN .

SCIENCE, 1998, 282 (5391) :1105-1107

[52] Growth of a single freestanding multiwall carbon nanotube on each nanonickel dot [J].

Ren, ZF ;

Huang, ZP ;

Wang, DZ ;

Wen, JG ;

Xu, JW ;

Wang, JH ;

Calvet, LE ;

Chen, J ;

Klemic, JF ;

Reed, MA .

APPLIED PHYSICS LETTERS, 1999, 75 (08) :1086-1088

[53]

Saito R., 1998, PHYS PROPERTIES CARB

[54] Electrocatalytic properties and sensor applications of fullerenes and carbon nanotubes [J].

Sherigara, BS ;

Kutner, W ;

D'Souza, F .

ELECTROANALYSIS, 2003, 15 (09) :753-772

[55] Electrochemical studies of polynucleotide binding and oxidation by metal complexes: Effects of scan rate, concentration, and sequence [J].

Sistare, MF ;

Holmberg, RC ;

Thorp, HH .

JOURNAL OF PHYSICAL CHEMISTRY B, 1999, 103 (48) :10718-10728

[56]

SKOOG DA, 1985, PRINCIPLES INSTRUMEN

[57] Carbon nanotube array-based biosensor [J].

Sotiropoulou, S ;

Chaniotakis, NA .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2003, 375 (01) :103-105

[58] N-HYDROXYSULFOSUCCINIMIDE ACTIVE ESTERS - BIS(N-HYDROXYSULFOSUCCINIMIDE) ESTERS OF 2 DICARBOXYLIC-ACIDS ARE HYDROPHILIC, MEMBRANE-IMPERMEANT, PROTEIN CROSS-LINKERS [J].

STAROS, JV .

BIOCHEMISTRY, 1982, 21 (17) :3950-3955

[59]

Tomanek D., 2000, SCI APPL NANOTUBES

[60] Ion-exchange voltammetry at polymer film-coated nanoelectrode ensembles [J].

Ugo, P ;

Moretto, LM ;

Bellomi, S ;

Menon, VP ;

Martin, CR .

ANALYTICAL CHEMISTRY, 1996, 68 (23) :4160-4165

← 1 2 3 4 5 6 7 →