PdCl2/NaI-catalyzed homodimeric coupling-cyclization reaction of 2,3-allenols:: An efficient synthesis of 4-(1',3'-dien-2'-yl)-2,5-dihydrofuran derivatives

被引：51

作者：

Deng, Youqian ^{[1
]}

Yu, Yihua ^{[2
]}

Ma, Shengming ^{[1
,3
]}

机构：

[1] Zhejiang Univ, Dept Chem, Lab Mol Recognit & Synth, Hangzhou 310027, Peoples R China

[2] E China Normal Univ, Dept Phys, Shanghai Key Lab Funct Magnet Resonance Imaging, Shanghai 200062, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 02期

关键词：

D O I：

10.1021/jo702332m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A PdCl2/NaI-catalyzed homodimeric coupling-cyclization reaction of 2,3-allenols was observed to provide an efficient route to 4-(1',3'-dien-2'-yl)-2,5-dihydrofuran derivatives. By using the easily available optically active starting materials, 2,5-dihydrofurans with high enantiopurity may be prepared. A Pd(II) catalyzed mechanism was also discussed.

引用

页码：585 / 589

页数：5

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