Stereoselective synthesis of the C(53)-C(67) polyene fragment of amphidinol 3

被引：21

作者：

Colobert, Francoise

Kreuzer, Thomas

Cossy, Janine

Reymond, Sebastien

Tsuchiya, Tomoki

Ferrie, Laurent

Marko, Istvan E.

Jourdain, Pierre

机构：

[1] Univ Strasbourg, CNRS, Lab Stereochim, ECPM, F-67087 Strasbourg 2, France

[2] CNRS, ESPCI, Chim Organ Lab, F-75231 Paris 05, France

[3] Catholic Univ Louvain, Dept Chim, B-1348 Louvain, Belgium

来源：

SYNLETT | 2007年 / 15期

关键词：

amphidinol; 3; natural products; total synthesis; reductive elimination; addition reactions;

D O I：

10.1055/s-2007-985601

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A stereoselective synthesis of the polyene fragment C(53)-C(67) of amphidinol 3 is described using a sequence of reduction, benzoylation, and reductive elimination for the stereospecific preparation of the polyene motif as key steps starting from acetylenic precursors.

引用

收藏

页码：2351 / 2354

页数：4

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