Postbinding functions of CD4 in HIV infection

被引:1
作者
Bachelder, RE [1 ]
Letvin, NL [1 ]
机构
[1] HARVARD UNIV, BETH ISRAEL HOSP,SCH MED,DEPT MED, DIV VIRAL PATHOGENESIS, BOSTON, MA 02215 USA
关键词
D O I
10.1016/0966-842X(96)10043-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several studies have suggested that the CD4 molecule, in addition to serving as the HIV receptor, may also be involved in postbinding events of HIV infection. The CD4 molecule has been shown to assume an altered conformation on the T-cell surface following HIV binding, which may be involved in these postbinding events.
引用
收藏
页码:359 / 363
页数:5
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