Rhodium-catalyzed addition-cyclization reactions of 5-Yn-1-ones with arylboronic acids

被引：42

作者：

Miura, T ^{[1
]}

Shimada, M ^{[1
]}

Murakami, M ^{[1
]}

机构：

[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Kyoto 6158510, Japan

来源：

SYNLETT | 2005年 / 04期

关键词：

rhodium; addition-cyclization reaction; nucleophilic addition; arylboronic acid; 5-yn-1-one;

D O I：

10.1055/s-2005-863718

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Yn-1-ones react with arylboronic acids in the presence of a catalytic amount of rhodium(I) complex having a diolefin ligand to afford 2-alkylidenecyclopentanols through the regioselective addition of an arylrhodium(I) species across the carbon-carbon triple bond, followed by intramolecular nucleophilic addition of the resulting vinylrhodium(I) species to the carbonyl group.

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收藏

页码：667 / 669

页数：3

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