Rapid microwave promoted sonogashira coupling reactions on solid phase

被引：57

作者：

Erdélyi, M

Gogoll, A

机构：

[1] Uppsala Univ, Dept Organ Chem, S-75124 Uppsala, Sweden

[2] Uppsala Univ, Dept Organ Pharmaceut Chem, S-75123 Uppsala, Sweden

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 16期

关键词：

D O I：

10.1021/jo034284s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A microwave-enhanced, rapid, and efficient solid-phase version of the Sonogashira reaction is presented. It has been applied to the coupling of aryl iodides and bromides with various acetylene derivatives giving excellent yields in 15-25 min. The scopes of homogeneous, solventless, and solid-phase conditions for Sonogashira. coupling of aryl halides are compared.

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页码：6431 / 6434

页数：4

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