High-speed optical frequency-domain imaging

被引:727
作者
Yun, SH
Tearney, GJ
de Boer, JF
Iftimia, N
Bouma, BE
机构
[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Wellman Labs Photomed, Boston, MA 02114 USA
来源
OPTICS EXPRESS | 2003年 / 11卷 / 22期
关键词
D O I
10.1364/OE.11.002953
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We demonstrate high-speed, high-sensitivity, high-resolution optical imaging based on optical frequency-domain interferometry using a rapidly-tuned wavelength-swept laser. We derive and show experimentally that frequency-domain ranging provides a superior signal-to-noise ratio compared with conventional time-domain ranging as used in optical coherence tomography. A high sensitivity of - 110 dB was obtained with a 6 mW source at an axial resolution of 13.5 mum and an A-line rate of 15.7 kHz, representing more than an order-of-magnitude improvement compared with previous OCT and interferometric imaging methods. (C) 2003 Optical Society of America.
引用
收藏
页码:2953 / 2963
页数:11
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