Room temperature ionic liquid promoted improved and rapid synthesis of 2,4,5-triaryl imidazoles from aryl aldehydes and 1,2-diketones or α-hydroxyketone

被引：291

作者：

Siddiqui, SA ^{[1
]}

Narkhede, UC ^{[1
]}

Palimkar, SS ^{[1
]}

Daniel, T ^{[1
]}

Lahoti, RJ ^{[1
]}

Srinivasan, KV ^{[1
]}

机构：

[1] Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON | 2005年 / 61卷 / 14期

关键词：

2,4,5-triaryl imidazoles; ionic liquid (IL); ammonium acetate; benzaldehydes; 1,2-diketones; alpha-hydroxyketone;

D O I：

10.1016/j.tet.2005.01.116

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved and rapid one-pot synthesis of 2,4,5-triaryl imidazoles in a room temperature ionic liquid is described, which does not need any added catalyst. Different ionic liquids based on 1-n-butyl and 1,3-di-n-butyl imidazolium salts were screened and their efficacy in terms of acidity and polarity have been correlated with yields and reaction period. The one-pot methodology resulting in excellent isolated yields in short reaction times is characterized by simple work up procedures and efficient recovery and recycling of the ionic liquid, which acts as a promoter. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：3539 / 3546

页数：8

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