Catheter-directed contrast-enhanced coronary MR angiography in swine using magnetization-prepared True-FISP

Contrast-enhanced (CE) coronary magnetic resonance angiography (MRA) following intraarterial (IA) injection of contrast agent was compared using two sequences in swine: magnetization-prepared fast imaging with steady-state precession (True-FISP), and magnetization-prepared fast low-angle shot (FLASH). Thick-slice projection images were acquired with submillimeter in-plane spatial resolution (0.9 x 0.8 mm(2)). The magnetization-preparation scheme provided a clear delineation of the major coronary arteries with excellent background suppression. The Trule-FISP acquisition resulted in an increase in signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) by approximately a factor of 2 over FLASH (P < 0.05). Magnetization-prepared True-FISP is a promising technique for catheter-directed CE thick-slice projection coronary MRA. (C) 2003 Wiley-Liss, Inc.