Multiple roles for DNA methylation in gametic imprinting

被引：54

作者：

Neumann, B ^{[1
]}

Barlow, DP ^{[1
]}

机构：

[1] INST MOLEC PATHOL,A-1030 VIENNA,AUSTRIA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1996年 / 6卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(96)80045-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Allele-specific DNA methylation has been observed for all tested imprinted genes and has a clear role in the imprinting mechanism. It remains to be resolved whether this role is to act as the gametic imprinting signal or to cause or maintain allele-specific expression.

引用

收藏

页码：159 / 163

页数：5

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