Regioselective ring metalation in [2,4]-bisoxazoles

被引：18

作者：

Williams, DR ^{[1
]}

Brooks, DA ^{[1
]}

Meyer, KG ^{[1
]}

Pagel, M ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, NMR & Mol Visualizat Facil, Bloomington, IN 47405 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 44期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(98)01792-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The efficient, highly regioselective metalation of a 2,4-disubstituted bisoxazole system is described. The resulting lithio-oxazole is a competent nucleophile in subsequent alkylations. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8023 / 8026

页数：4

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