Application of chiral bidentate NMR solvents for assignment of the absolute configuration of alcohols: scope and limitation

被引：22

作者：

Kobayashi, Y ^{[1
]}

Hayashi, N ^{[1
]}

Kishi, Y ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 40期

基金：

美国国家卫生研究院;

关键词：

absolute configuration; chiral NMR solvent; NMR database;

D O I：

10.1016/j.tetlet.2003.08.022

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The C-13 NMR behaviors of several cyclic and biaryl secondary alcohols as well as acyclic tertiary alcohols have been studied in the chiral bidentate NMR solvent BMBA-p-Me (1). An empirical rule has been advanced to correlate the absolute configuration of each type of alcohols with the C-13 chemical shift behaviors in (R,R)- and (S,S)-BMBA-p-Me. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：7489 / 7491

页数：3

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