YLR209c encodes Saccharomyces cerevisiae purine nucleoside phosphorylase

被引：29

作者：

Lecoq, K

Belloc, I

Desgranges, C

Konrad, M

Daignan-Fornier, B

机构：

[1] Inst Biochim & Genet Cellulaires, CNRS UMR 5095, F-33077 Bordeaux, France

[2] Max Planck Inst Biophys Chem, Dept Mol Genet, D-37070 Gottingen, Germany

[3] INSERM U441, F-33600 Pessac, France

来源：

JOURNAL OF BACTERIOLOGY | 2001年 / 183卷 / 16期

关键词：

D O I：

10.1128/JB.183.16.4910-4913.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The yeast YLR209c (PNP1) gene encodes a protein highly similar to purine nucleoside phosphorylases. This protein specifically metabolized inosine and guanosine. Disruption of PNP1 led to inosine and guanosine excretion in the medium, thus showing that PNP1 plays an important role in the metabolism of these purine nucleosides in vivo.

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页码：4910 / 4913

页数：4

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