Lung air spaces:: MR imaging evaluation with hyperpolarized 3He gas

被引：214

作者：

de Lange, EE

Mugler, JP

Brookeman, JR

Knight-Scott, J

Truwit, JD

Teates, CD

Daniel, TM

Bogorad, PL

Cates, GD

机构：

[1] Univ Virginia, Ctr Hlth Sci, Dept Radiol, Charlottesville, VA 22908 USA

[2] Univ Virginia, Ctr Hlth Sci, Dept Internal Med, Charlottesville, VA 22908 USA

[3] Univ Virginia, Ctr Hlth Sci, Dept Surg, Charlottesville, VA 22908 USA

[4] Magnet Imaging Technol, Durham, NC USA

[5] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

来源：

RADIOLOGY | 1999年 / 210卷 / 03期

关键词：

helium; lung; MR; magnetic resonance (MR); contrast enhancement; nuclei other than H;

D O I：

10.1148/radiology.210.3.r99fe08851

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Thirty-two magnetic resonance imaging examinations of the lungs were performed in 16 subjects after inhalation of 1-2 L of helium 3 gas that was laser polarized to 10%-25%. The distribution of the gas was generally uniform, with visualization of the fissures in most cases. Ventilation defects were demonstrated in smokers and in a subject with allergies. The technique has potential for evaluating small airways disease.

引用

页码：851 / 857

页数：7

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