Studies on total syntheses of antitumor styryllactones: Stereoselective total syntheses of (+)-goniofufurone, (+)-goniobutenolide A, and (-)-goniobutenolide B

被引：52

作者：

Mukai, C ^{[1
]}

Hirai, S ^{[1
]}

Kim, IJ ^{[1
]}

Kido, M ^{[1
]}

Hanaoka, M ^{[1
]}

机构：

[1] OTSUKA PHARMACEUT CO LTD,TOKUSHIMA INST NEW DRUG RES 2,MED CHEM,TOKUSHIMA 77101,JAPAN

来源：

TETRAHEDRON | 1996年 / 52卷 / 19期

关键词：

D O I：

10.1016/0040-4020(96)00296-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereoselective aldol reaction of the aldehyde 11, derived from (+)-tricarbonyl(eta(6)-2-trimethylsilylbenzaldehyde)chromium(0) complex (4), with 2-trimethysilyloxyfuran afforded the gamma-lactone derivative 13. The gamma-lactone 13 was subsequently convened into three antitumor styryllactones, (+)-goniofufurone, (+)-goniobutenolide A, and (-)-goniobutenolide B. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6547 / 6560

页数：14

共 44 条

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