Ti(IV)/BINOL-catalyzed asymmetric aldol reaction of a masked acetoacetic ester: pronounced influence of catalyst concentration on nonlinear effects

被引：13

作者：

De Rosa, M ^{[1
]}

Acocella, MR ^{[1
]}

Villano, R ^{[1
]}

Soriente, A ^{[1
]}

Scettri, A ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, Salerno, Italy

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 32期

关键词：

asymmetric aldol reaction; titanium complex; binaphthol; nonlinear effects; O-silyldienolate;

D O I：

10.1016/S0040-4039(03)01470-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Initial concentration of enantioenriched or enantiopure catalysts proved to be an important factor for the achievement of a more pronounced amplification of ee's in the Ti(IV)/BINOL-catalyzed aldol reaction of an O-silyldienolate. (C) 2003 Elsevier Ltd. All rights reserved.

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收藏

页码：6087 / 6090

页数：4

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