Solid phase synthesis of aryl-ether dendrimers

被引：37

作者：

Basso, A

Evans, B

Pegg, N

Bradley, M ^{[1
]}

机构：

[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

[2] Glaxo Wellcome Res & Dev Ltd, Stevenage SG1 2NY, Herts, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 08期

关键词：

D O I：

10.1039/b100003i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Solid phase chemistry can be used to prepare, in excellent yield and purity, a range of Frechet-type aryl-ether dendrimers, for use in either dendrimer conjugation studies, resin loading enhancement or the wedge based synthesis of larger dendrimers.

引用

页码：697 / 698

页数：2

共 11 条

[1]

Ashton PR, 1998, CHEM-EUR J, V4, P781, DOI 10.1002/(SICI)1521-3765(19980515)4:5<781::AID-CHEM781>3.0.CO

[2]

2-3

[3]

Basso A, 2000, EUR J ORG CHEM, V2000, P3887, DOI 10.1002/1099-0690(200012)2000:23<3887::AID-EJOC3887>3.0.CO

[4]

2-T

[5] Solid-phase synthesis of aryl ethers on high loading dendrimer resin [J].

Basso, A ;

Evans, B ;

Pegg, N ;

Bradley, M .

TETRAHEDRON LETTERS, 2000, 41 (19) :3763-3767

[6] Linkers and cleavage strategies in solid-phase organic synthesis and combinatorial chemistry [J].

Guillier, F ;

Orain, D ;

Bradley, M .

CHEMICAL REVIEWS, 2000, 100 (06) :2091-2157

[7] A NEW CONVERGENT APPROACH TO MONODISPERSE DENDRITIC MACROMOLECULES [J].

HAWKER, CJ ;

FRECHET, JMJ .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (15) :1010-1013

[8] A photolabile carbamate based dual linker analytical construct for facile monitoring of solid phase chemistry: 'TLC' for solid phase? [J].

McKeown, SC ;

Watson, SP ;

Carr, RAE ;

Marshall, P .

TETRAHEDRON LETTERS, 1999, 40 (12) :2407-2410

[9] Solid-phase dendrimer synthesis and the generation of super-high-loading resin beads for combinatorial chemistry [J].

Swali, V ;

Wells, NJ ;

Langley, GJ ;

Bradley, M .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (15) :4902-4903

[10]

Wells NJ, 1998, BIOPOLYMERS, V47, P381, DOI 10.1002/(SICI)1097-0282(1998)47:5<381::AID-BIP5>3.0.CO

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