Comparative Evaluation of a Chromogenic Agar Medium, the Modified Hodge Test, and a Battery of Meropenem-Inhibitor Discs for Detection of Carbapenemase Activity in Enterobacteriaceae

被引：35

作者：

Seah, Christine

Low, Donald E. ^{[2
,3
]}

Patel, Samir N. ^{[2
]}

Melano, Roberto G. ^{[1
,2
,3
]}

机构：

[1] Ontario Agcy Hlth Protect & Promot, Publ Hlth Lab Branch, Toronto, ON M9P 3T1, Canada

[2] Univ Toronto, Toronto, ON, Canada

[3] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 05期

关键词：

METALLO-BETA-LACTAMASE; CLASS-A CARBAPENEMASE; KLEBSIELLA-PNEUMONIAE; PSEUDOMONAS-AERUGINOSA; ERTAPENEM RESISTANCE; ASSAYS; ACID;

D O I：

10.1128/JCM.00203-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Three phenotypic methods (modified Hodge test, chromogenic agar, and meropenem discs combined with specific inhibitors) used for the detection of carbapenemase activity were tested on a panel of characterized Enterobacteriaceae expressing various beta-lactamase mechanisms. Overall, the meropenem-plus-inhibitor approach was more sensitive and specific than the other methods, despite its limitation of being unable to detect class D carbapenemases.

引用

页码：1965 / 1969

页数：5

共 23 条

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