Protein surface recognition by rational design: Nanomolar ligands for potassium channels

被引:56
作者
Gradl, SN
Felix, JP
Isacoff, EY
Garcia, ML
Trauner, D [1 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Ctr New Direct Organ Synth, Berkeley, CA 94720 USA
[2] Merck Res Labs, Dept Ion Channels, Rahway, NJ 07065 USA
[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
关键词
D O I
10.1021/ja036155z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The rational design and development of four-fold symmetrical ligands for potassium channels is described. Copyright © 2003 American Chemical Society.
引用
收藏
页码:12668 / 12669
页数:2
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