Anion-mediated phase transfer of zinc(II)-coordinated tyrosine derivatives

被引:36
作者
Jiang, H [1 ]
O'Neil, EJ [1 ]
DiVittorio, KM [1 ]
Smith, BD [1 ]
机构
[1] Univ Notre Dame, Dept Chem & Biochem, Notre Dame, IN 46556 USA
关键词
D O I
10.1021/ol0510421
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Tyrosine-derived Zn2+ coordination complexes and their fluorescent NBD conjugates are synthesized in a short, high-yielding procedure. The Zn2+ complexes are highly water soluble, but in the presence of sodium laurate they readily transfer into an octanol layer. Furthermore, the NBD-labeled bis-Zn2+ complex can partition into vesicle membranes containing anionic phospholipids.
引用
收藏
页码:3013 / 3016
页数:4
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