Novel phosphorus radical-based routes to horsfiline

被引：57

作者：

Murphy, JA ^{[1
]}

Tripoli, R ^{[1
]}

Khan, TA ^{[1
]}

Mail, UW ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, Glasgow G1 1XL, Lanark, Scotland

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 15期

关键词：

D O I：

10.1021/ol051095i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Radicals derived from the phosphorus reagents, ethylpiperidine hypophosphite (EPHP) and diethylphosphine oxide (DEPO), are used in two related approaches to synthesis of the alkaloid horsfiline (1). In particular, DEPO proves beneficial for effecting cyclizations at 80 degrees C that are difficult or impossible with BU3SnH.

引用

页码：3287 / 3289

页数：3

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