A rapid synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans

被引：39

作者：

Kuethe, JT ^{[1
]}

Wong, A ^{[1
]}

Journet, M ^{[1
]}

Davies, IW ^{[1
]}

机构：

[1] Merck & Co Inc, Dept Proc Res, Rahway, NJ 07065 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 09期

关键词：

D O I：

10.1021/jo0500941

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An effective strategy has been developed for the rapid and efficient one-pot synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans from readily available o-nitrotoluenes and aromatic aldehydes. This strategy allows access to a structurally diverse array of products for further manipulation.

引用

页码：3727 / 3729

页数：3

共 63 条

[61] A convenient ring formation of 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans from phenols and 2-aryl-2,2-dialkylacetaldehydes [J].