The Continuous-Flow Synthesis of Carboxylic Acids using CO2 in a Tube-In-Tube Gas Permeable Membrane Reactor

被引：206

作者：

Polyzos, Anastasios ^{[1
]}

O'Brien, Matthew ^{[1
]}

Petersen, Trine P. ^{[1
]}

Baxendale, Ian R. ^{[1
]}

Ley, Steven V. ^{[1
]}

机构：

[1] Univ Cambridge, Innovat Technol Ctr, Dept Chem, Cambridge CB1 2EW, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 05期

基金：

英国工程与自然科学研究理事会;

关键词：

carbon dioxide; flow chemistry; gas-liquid reactions; microreactor; polymer-supported reagents; MICROREACTORS; TRANSPORT; REAGENTS; POTENT;

D O I：

10.1002/anie.201006618

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Keep it simple: A gas-liquid flow reactor has been developed based on a gas permeable tube-in-tube configuration which effectively delivers gas to a liquid substrate stream in a safe, continuous fashion. A series of carboxylic acids were prepared from the reaction of CO2 with a range of Grignard reagents (see picture). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1190 / 1193

页数：4

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