Tunable, monochromatic x-rays: An enabling technology for molecular/cellular imaging and therapy

被引:29
作者
Carroll, F [1 ]
机构
[1] Vanderbilt Univ, Med Ctr, Nashville, TN 37235 USA
关键词
monochromatic X-rays; k-edge; Auger cascade; crystallography; mammography;
D O I
10.1002/jcb.10632
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pulsed, tunable, monochromatic X-rays hold great potential as a cellular and molecular probe. These beams can be tuned to the binding energy of orbital electrons in atoms, making them extremely useful in diagnostic k-edge imaging and Auger cascade radiotherapy. Their wide tunability makes them ideal for the performance of various techniques as disparate as protein crystallography and three-dimensional, compressionless, monochromatic mammography. Since only the frequency best suited to the task at hand is used, radiation exposure to patients or animals is exceedingly low when compared to standard X-ray techniques. (C) 2003 Wiley-Liss, Inc.
引用
收藏
页码:502 / 508
页数:7
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